According to the research, these mitochondrial DNA insertions could be linked to early death.
Mitochondria in brain cells frequently insert their “The mitochondrial DNA behaves similar to a beyond energy production. “Mitochondria are cellular processors and a mighty signaling platform,” Picard says. “We knew they could control which genes are turned on or off. Now we know mitochondria can even change the nuclear DNA sequence itself.” Reference: “Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts” by Weichen Zhou, Kalpita R. Karan, Wenjin Gu, Hans-Ulrich Klein, Gabriel Sturm, Philip L. De Jager, David A. Bennett, Michio Hirano, Martin Picard and Ryan E. Mills, 22 August 2024, DOI: 10.1371/journal.pbio.3002723 This work was supported by grants from the U.S. 
/https://tf-cmsv2-smithsonianmag-media.s3.amazonaws.com/filer_public/d1/82/d18228f6-d319-4525-bb18-78b829f0791f/mammalevolution_web.jpg "How to Make a Mammal in Nine Evolutionary Steps")
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