Researchers at MIT have developed a water-soluble version of the bacterial enzyme histidine kinase, which is a promising target for new antibiotics due to its unique presence in bacteria. The modified enzyme retains its natural functions and could be crucial in combating antibiotic resistance, which claims over a million lives annually. Credit: SciTechDaily.com
Scientists created a water-soluble version of an important bacterial enzyme, which can now be used in drug screens to identify new antibiotics.
DOI: 10.1038/s41467-024-48513-9
The research was funded, in part, by the National Natural Science Foundation of China.