Team’s approach reveals crucial role played by a specific enzyme in the folding process.
While we often think of diseases as caused by foreign bodies—bacteria or viruses—there are hundreds of diseases affecting humans that result from errors in cellular production of its proteins. A team of researchers led by the University of Massachusetts Amherst recently leveraged the power of cutting-edge technology, including an innovative technique called glycoproteomics, to unlock the carbohydrate-based code that governs how certain classes of proteins form themselves into the complex shapes necessary to keep us healthy.
Unraveling the Mysteries of Serpins
The research, published in the journal DOI: 10.1016/j.molcel.2023.11.006