Groundbreaking research has led to the creation of threofuranosyl nucleic acid (TNA), offering enhanced stability and therapeutic potential, with applications in drug delivery and diagnostics. Credit: SciTechDaily.com
Groundbreaking research has led to the creation of threofuranosyl nucleic
Structural comparison of DNA and the artificial TNA, a Xeno nucleic acid with the natural base pairs AT and GC and an additional base pair (XY). Credit: Stephanie Kath-Schorr
Potential of Artificial Nucleic Acids
Artificial nucleic acids differ in structure from their originals. These changes affect their stability and function.
“Our threofuranosyl nucleic acid is more stable than the naturally occurring nucleic acids DNA and DOI: 10.1021/jacs.3c14626