Research from Monash University indicates that high levels of ‘good cholesterol’ (HDL-C) are associated with an increased risk of dementia in the elderly, highlighting a need for more in-depth study in this area.
Abnormally high levels of HDL-C, colloquially known as ‘good cholesterol’, are associated with an increased risk of dementia in older adults, a Monash University-led study has found.
Researchers said very high levels of HDL-C linked to dementia risk in this study were uncommon and not diet related, but more likely to reflect a metabolic disorder.
The findings may help doctors to recognize a group of older patients potentially at risk of dementia, particularly in those aged 75 and older.
Findings in Elderly Populations
Published in DOI: 10.1016/j.lanwpc.2023.100963
*The Aspirin in Reducing Events in the Elderly (ASPREE) trial is a double-blind, randomised, placebo-controlled trial of daily aspirin in healthy older people. ASPREE recruited 16,703 participants aged ≥70 years (from Australia) and 2,411 participants aged ≥65 years (from the US) between 2010 and 2014. Participants had no diagnosed